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RNAkeep Reagent is a novel technology for immediate preservation of the gene expression pattern in animal tissues, enabling reliable gene expression analysis. After harvesting, tissues are immediately submerged in RNAkeep Reagent, which rapidly permeates the tissues to stabilize and protect cellular RNA in situ.
The reagent preserves RNA for up to 1 day at 37°C, 7 days at 15–25°C, or 4 weeks at 2–8°C, allowing transportation, storage, and shipping of samples without ice or dry ice. Alternatively, the samples can be archived at –20°C or –80°C. During storage or transport in RNAkeep Reagent, even at elevated temperatures (e.g., room temperature or 37°C), the cellular RNA remains intact and undegraded. RNAkeep technology allows large numbers of samples to be easily processed and replaces inconvenient, dangerous, and equipment-intensive methods, such as snap-freezing of samples in liquid nitrogen, storage at –80°C, cutting and weighing on dry ice, or immediate processing of harvested samples. RNAkeep Reagent can be used for various animal tissues, including brain, heart, kidney, spleen, lung, liver, thymus, etc.